Penna San Giovanni rises to 630 m a.s.l. located close to a rocky spur between the valleys of the Salino and Tennacola rivers. Surrounded by a high hill countryside, it dominates the territory from the Sibillini Mountains to the Adriatic coast.

Its location, the views, the healthy air and the precious architectural works, such as the eighteenth-century and entirely wooden Teatro Comunale, make this town a pearl of the ancient Marca Fermana.